Clinical Features and Antibiotic Susceptibility of Culture-proven Infectious Keratitis: a Multicenter 10-year Study

نویسندگان

چکیده

ëª©ì  최근 10ë „ê°„ 감염각막염 중 배양검사상 ê· ì£¼ê°€ 확인된 환자에 대하여 여러 임상양상에 대해 ì•Œì•„ë³´ê³ ìž 한다. 대상과 방법 2008ë „ 1월부터 2017ë 12월까지 ì „êµ­ 8개 병원에서 956ëª ì˜ 의무기록을 í›„í–¥ì ìœ¼ë¡œ 분석하여, ì„ í–‰ìš”ì¸, ì›ì¸ê· , 치료 방법, 예후 등을 분석하였다. ê²°ê³¼ 감염각막염의 가장 흔한 행요인은 안외상(33.2%)이었다. ì´ˆê¸°ì‹œë ¥ì€ ì•ˆì „ìˆ˜ì§€ 이하가 449안(47.0%)이었다. 각막궤양은 중심부에서 í”í•˜ì˜€ê³ í¬ê¸°ëŠ” 4 mm2 많았다. „방축농이 동반된 경우는 295안(30.9%)이었다. 배양된 주는 총 1,039ê· ìœ¼ë¡œ ê·¸ëžŒìŒì„±ê· 443ê· ì£¼(42.6%)가 은 ë ¹ë†ê· ê·¸ëžŒì–‘ì„±ê· í”¼ë¶€í¬ë„ì•Œê· ì§„ê· í‘¸ì‚¬ë¥¨ì´ì—ˆë‹¤. ìˆ˜ìˆ ì¹˜ë£ŒëŠ” 201안(21.0%)에서 ì–‘ë§‰ì´ì‹ìˆ 66안, ì•ˆêµ¬ë‚´ìš©ì œê±°ìˆ 44안 순이었다. ìµœì¢ ì‹œë 0.2보다 좋은 ¥ì´ 422안(44.1%)이었다. ëª©ì‹œí”Œë¡ì‚¬ì‹ ê³¼ ë°˜ì½”ë§ˆì´ì‹ ì—, ˆë³´í”Œë¡ì‚¬ì‹ 세프타지딤에 높은 감수성을 보였지만 일부 ìž¥ì•Œê· ìŠˆë„ëª¨ë‚˜ìŠ¤ 등에서 €í•­ì„±ì„ 보였다. ê²°ë¡ êµ­ë‚´ 감염각막염은 안외상으로 흔히 ë°œìƒí•˜ì˜€ê³ ì´ ëŒ€í‘œì ì¸ ìž ì› 후 약물 및 치료로 í˜¸ì „ëœ 경우가 많았지만 보이는 ì„¸ê· ì— 대해서는 주의가 필요하다. 에서 불량한 임상결과에 이르는 위험인자는 ¥ 0.02 미만, „방축농, 65세 이상 나이, 각막중심부 ê¶¤ì–‘ì´ì—ˆê³ 70세 나이였다. Keywords: Fusarium, Keratitis, Microbial sensitivity tests, Pseudomonas aeruginosa, Staphylococcus epidermidis

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ژورنال

عنوان ژورنال: Journal of The Korean Ophthalmological Society

سال: 2021

ISSN: ['0378-6471', '2092-9374']

DOI: https://doi.org/10.3341/jkos.2021.62.4.447